Blar i SIHF Open Archive på forfatter "Bjørklund, Geir"
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Arsenic toxicity: Molecular targets and therapeutic agents
Nurchi, Valeria Marina; Djordjevic, Aleksandra Buha; Crisponi, Guido; Alexander, Jan; Bjørklund, Geir; Aaseth, Jan (Peer reviewed; Journal article, 2020)High arsenic (As) levels in food and drinking water, or under some occupational conditions, can precipitate chronic toxicity and in some cases cancer. Millions of people are exposed to unacceptable amounts of As through ... -
Cerebral hypoperfusion in autism spectrum disorder
Bjørklund, Geir; Kern, Janet K; Urbina, Mauricio A.; Saad, Khaled; El-Houfey, Amira A.; Geier, David A.; Chirumbolo, Salvatore; Geier, Mark R.; Mehta, Jyutika A.; Aaseth, Jan (Peer reviewed; Journal article, 2018)Cerebral hypoperfusion, or insufficient blood flow in the brain, occurs in many areas of the brain in patients diagnosed with autism spectrum disorder (ASD). Hypoperfusion was demonstrated in the brains of individuals with ... -
Chronic fatigue syndrome (CFS): Suggestions for a nutritional treatment in the therapeutic approach
Bjørklund, Geir; Dadar, Maryam; Pen, Joeri J.; Chirumbolo, Salvatore; Aaseth, Jan (Peer reviewed; Journal article, 2019)Chronic fatigue syndrome (CFS) is known as a multi-systemic and complex illness, which induces fatigue andlong-term disability in educational, occupational, social, or personal activities. The diagnosis of this disease ... -
Iron Deficiency in Obesity and After Bariatric Surgery
Bjørklund, Geir; Peana, Massimiliano; Pivina, Lyudmila; Dosa, Alexandru; Aaseth, Jan; Semenova, Yuliya; Chirumbolo, Salvatore; Medici, Serenella; Dadar, Maryam; Costea, Daniel-Ovidiu (Peer reviewed; Journal article, 2021)Iron deficiency (ID) is particularly frequent in obese patients due to increased circulating levels of acute-phase reactant hepcidin and adiposity-associated inflammation. Inflammation in obese subjects is closely related ... -
Mercury exposure and its effects on fertility and pregnancy outcome
Bjørklund, Geir; Chirumbolo, Salvatore; Dadar, Maryam; Pivina, Lyudmila; Lindh, Ulf; Butnariu, Monica; Aaseth, Jan (Peer reviewed; Journal article, 2019)Mercury (Hg), a highly toxic environmental pollutant, shows harmfulness which still represents a big concern for human health, including hazards to fertility and pregnancy outcome. Research has shown that Hg could induce ... -
A review on coordination properties of thiol-containing chelating agents towards mercury, cadmium, and lead
Bjørklund, Geir; Crisponi, Guido; Nurchi, Valeria Marina; Cappai, Rosita; Djordjevic, Aleksandra Buha; Aaseth, Jan (Peer reviewed; Journal article, 2019)Abstract: The present article reviews the clinical use of thiol-based metal chelators in intoxications and overexposure with mercury (Hg), cadmium (Cd), and lead (Pb). Currently, very few commercially available pharmaceuticals ... -
Xenobiotics, trace metals and genetics in the pathogenesis of tauopathies
Aaseth, Jan; Buha, Aleksandra; Wallace, David R.; Bjørklund, Geir (Peer reviewed; Journal article, 2020)Tauopathies are a disease group characterized by either pathological accumulation or release of fragments of hyperphosphorylated tau proteins originating from the central nervous system. The tau hypotheses of Parkinson’s ...